QB Nick Foles

After breaking his collarbone in Week 1 against the Chiefs, Minshew Mania took over and it looked like Foles was going to be the backup once he was healthy. But, during the Jaguars’ Week 10, head coach Doug Marrone said that Foles will be the starter against the Colts in Week 11. He put up solid numbers, throwing for 296 yards, 2 touchdowns, and an interception, but he’s still settling in. Foles and the Jaguars take on an exceptional Titans secondary in Week 12.

RB Jonathan Williams

Williams was only active because Wilkins was inactive due to ankle problems and took over as the ball-carrier after Mack broke his hand and dominated the Jaguars. Williams only got 13 carries and rushed for 116 yards. He’ll have a tougher matchup against the Texans in Week 12, but he should get the majority of the carries with some redzone touches. 

RB Jaylen Samuels

With Connor’s season riddled with injuries, owning Samuels is a must. In Week 11 against the Browns, Connor went down with an injury and Samuels took over for him, getting 5 carries for 26 yards and catching 5 passes for 19 yards and a touchdown. Samuels and the Steelers have a much easier matchup in Week 12 when they visit the winless Bengals.

WR Deebo Samuel

With both Kittle and Sanders looking questionable for Week 12, Samuel will be Garoppolo’s favorite target on the field. He’s posted back-to-back 100+ yard games with 21 targets in both games combined with both Kittle and Sanders out. Samuel and the 49ers host a tough Packers defense at home in Week 12.

TE Ryan Griffin

With Herndon back on the injured reserve, Griffin will take over as the go-to tight end. He should continue to see around 5 targets a game against mediocre defenses since the Jets offense is weird to say the least. Last game, the Jets were actually competent on offense with Griffin catching all 5 of his targets for 109 yards and a touchdown against the Redskins. He’ll have an even more favorable matchup in Week 12 when the Jets play the Raiders.

Honorable Mention:  RB Bo Scarbrough

With Kerryon Johnson’s season over from of a knee injury, a committee’s been filling in for him. Unfortunately, none of them have been able to run the ball efficiently. Enter Bo Scarbrough; recently added onto the roster, Scarbrough got the majority of the touches and wasn’t terrible, totaling 14 carries for 55 yards and a touchdown against the Cowboys in Week 11. He looks to continue this trend into Week 12 when the Lions take on the Redskins.